Publications 2019/20
genOway has been acknowledged in numerous articles for the generation of mouse, rat, and cell line models.
Here, a selection of these publications:
Jing Wang, Gangadhara R Sareddy, Yujiao Lu, Uday P Pratap, Fulei Tang, Karah M Greene, Pornjittra L Meyre, Rajeshwar R Tekmal, Ratna K Vadlamudi, Darrell W Brann.
Astrocyte-Derived Estrogen Regulates Reactive Astrogliosis and is Neuroprotective following Ischemic Brain Injury.
J Neurosci. 2020 Dec 9
Caitlin Schneider, Connie Shen, Angelica A Gopal, Todd Douglas, Benjamin Forestell, Keith D Kauffman, Dakota Rogers, Patricio Artusa, Qian Zhang, Huie Jing, Alexandra F Freeman, Daniel L Barber, Irah L King, Maya Saleh, Paul W Wiseman, Helen C Su, Judith N Mandl.
Migration-induced cell shattering due to DOCK8 deficiency causes a type 2-biased helper T cell response.
Nat Immunol. 2020 Dec
Jumpei Kondo, Won Jae Huh, Jeffrey L Franklin, Michael C Heinrich, Brian P Rubin, Robert J Coffey.
A smooth muscle-derived, Braf-driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell-of-origin.
J Pathol. 2020 Dec
Natalie K Rynkiewicz, Karen E Anderson, Sabine Suire, Daniel M Collins, Eleftherios Karanasios, Oscar Vadas, Roger Williams, David Oxley, Jonathan Clark, Len R Stephens, Phillip T Hawkins.
Gβγ is a direct regulator of endogenous p101/p110γ and p84/p110γ PI3Kγ complexes in mouse neutrophils.
Sci Signal. 2020 Nov 3
Huijing Xia, Zhen Li, Thomas E Sharp 3rd, David J Polhemus, Jean Carnal, Karl H Moles, Ya-Xiong Tao, John Elrod, Josef Pfeilschifter, Karl-Friedrich Beck, David J Lefer.
Endothelial Cell Cystathionine γ-Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury.
J Am Heart Assoc. 2020 Oct 20
Silvia Pontis, Francesca Palese, Maria Summa, Natalia Realini, Massimiliano Lanfranco, Claudia De Mei, Daniele Piomelli.
N-Acylethanolamine Acid Amidase contributes to disease progression in a mouse model of multiple sclerosis.
Pharmacol Res. 2020 Oct
Amos Fumagalli, Joyce Heuninck, Anne Pizzoccaro, Enora Moutin, Joyce Koenen, Martial Séveno, Thierry Durroux, Marie-Pierre Junier, Géraldine Schlecht-Louf, Francoise Bachelerie, Dagmar Schütz, Ralf Stumm, Martine J Smit, Nathalie C Guérineau, Séverine Chaumont-Dubel, Philippe Marin.
The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication.
Nat Commun. 2020 Sep 25
Alyssa Grogan, Andrew Coleman, Humberto Joca, Henk Granzier, Mark W Russel, Christopher W Ward, Aikaterini Kontrogianni-Konstantopoulos.
Deletion of obscurin immunoglobulin domains Ig58/59 leads to age-dependent cardiac remodeling and arrhythmia.
Basic Res Cardiol. 2020 Sep 10
Julia Schuld, Zacharias Orfanos, Frédéric Chevessier, Britta Eggers, Lorena Heil, Julian Uszkoreit, Andreas Unger, Gregor Kirfel, Peter F M van der Ven, Katrin Marcus, Wolfgang A Linke, Christoph S Clemen, Rolf Schröder, Dieter O Fürst.
Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation.
Acta Neuropathol Commun. 2020 Sep 4
Sharon O Jensen-Cody, Kyle H Flippo, Kristin E Claflin, Yavuz Yavuz, Sarah A Sapouckey, Grant C Walters, Yuriy M Usachev, Deniz Atasoy, Matthew P Gillum, Matthew J Potthoff.
FGF21 Signals to Glutamatergic Neurons in the Ventromedial Hypothalamus to Suppress Carbohydrate Intake.
Cell Metab. 2020 Aug 4
N Yacov, P Kafri, Y Salem, O Propheta-Meiran, B Feldman, E Breitbart, I Mendel.
MOSPD2 is a therapeutic target for the treatment of CNS inflammation.
Clin Exp Immunol. 2020 Aug
Patricia Aparicio-Domingo, Hélène Cannelle, Matthew B Buechler, Sylvain Nguyen, Sandra M Kallert, Stéphanie Favre, Nagham Alouche, Natalie Papazian, Burkhard Ludewig, Tom Cupedo, Daniel D Pinschewer, Shannon J Turley, Sanjiv A Luther.
Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T-cell responses to acute and chronic viral infection.
Eur J Immunol. 2020 Jul 22
Lu Long, Xudong Yang, Mark Southwood, Stephen Moore, Alexi Crosby, Paul D Upton, Benjamin J Dunmore, Nicholas W Morrell.
Targeting translational read-through of premature termination mutations in BMPR2 with PTC124 for pulmonary arterial hypertension.
Pulm Circ. 2020 Jul 20
Amanda Haage, Kelsey Wagner, Wenjun Deng, Bhavya Venkatesh, Caitlin Mitchell, Katharine Goodwin, Aaron Bogutz, Louis Lefebvre, Catherine D Van Raamsdonk, Guy Tanentzapf.
Precise coordination of cell-ECM adhesion is essential for efficient melanoblast migration during development.
Development. 2020 Jul 17
Xiuli Zhang, Tingwen Guan, Boxuan Yang, Harvest F Gu, Zhihong Chi.
Effects of ZnT8 on epithelial-to-mesenchymal transition and tubulointerstitial fibrosis in diabetic kidney disease.
Cell Death Dis. 2020 Jul 17
Zeyuan Zhang, Qingwen Qian, Mark Li, Fan Shao, Wen-Xing Ding, Vitor A Lira, Sophia X Chen, Sara C Sebag, Gökhan S Hotamisligil, Huojun Cao, Ling Yang.
The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB.
Autophagy. 2020 Jul 15
Eleni Georgiadou, Elizabeth Haythorne, Matthew T Dickerson, Livia Lopez-Noriega, Timothy J Pullen, Gabriela da Silva Xavier, Samuel P X Davis, Aida Martinez-Sanchez, Francesca Semplici, Rosario Rizzuto, James A McGinty, Paul M French, Matthew C Cane, David A Jacobson, Isabelle Leclerc, Guy A Rutter.
The Pore-Forming Subunit MCU of the Mitochondrial Ca 2+ Uniporter Is Required for Normal Glucose-Stimulated Insulin Secretion in Vitro and in Vivo in Mice.
Diabetologia. 2020 Jul.
Enrique Calvo, Sara Cogliati, Pablo Hernansanz-Agustín, Marta Loureiro-López, Adela Guarás, Rafael A Casuso, Fernando García-Marqués, Rebeca Acín-Pérez, Yolanda Martí-Mateos, J C Silla-Castro, Marta Carro-Alvarellos, Jesús R Huertas, Jesús Vázquez, J A Enríquez.
Functional role of respiratory supercomplexes in mice: SCAF1 relevance and segmentation of the Q pool.
Sci Adv. 2020 Jun 24
Clement Soleilhavoup, Marco Travaglio, Kieran Patrick, Pedro Garção, Elangovan Boobalan, Youri Adolfs, Ruth V Spriggs, Emma Moles-Garcia, Dalbir Dhiraj, Tony Oosterveen, Sarah L Ferri, Ted Abel, Edward S Brodkin, R Jeroen Pasterkamp, Brian P Brooks, Lia Panman.
Nolz1 Expression Is Required in Dopaminergic Axon Guidance and Striatal Innervation.
Nat Commun. 2020 Jun 19.
L Francisco Lorenzo-Martín, Sonia Rodríguez-Fdez, Salvatore Fabbiano, Antonio Abad, María C García-Macías, Mercedes Dosil, Myriam Cuadrado, Javier Robles-Valero, Xosé R Bustelo.
Vav2 Pharmaco-Mimetic Mice Reveal the Therapeutic Value and Caveats of the Catalytic Inactivation of a Rho Exchange Factor.
Oncogene. 2020 Jun 11.
Henri-Philippe Konan, Loay Kassem, Soleilmane Omarjee, Ausra Surmieliova-Garnès, Julien Jacquemetton, Elodie Cascales, Amélie Rezza, Olivier Trédan, Isabelle Treilleux, Coralie Poulard, Muriel Le Romancer.
ERα-36 Regulates Progesterone Receptor Activity in Breast Cancer.
Breast Cancer Res. 2020 May 19.
Ravit Gabay Yehezkely, Shelly Zaffryar-Eilot, Anna Kaganovsky, Nurit Fainshtain Malka, Rohtem Aviram, Ido Livneh, Peleg Hasson.
Intracellular Role for the Matrix-Modifying Enzyme Lox in Regulating Transcription Factor Subcellular Localization and Activity in Muscle Regeneration.
Dev Cell. 2020 May 18.
Xiang Yi Kong, Erik Sebastian Vik, Meh Sameen Nawaz, Natalia Berges, Tuva Børresdatter Dahl, Cathrine Vågbø, Rajikala Suganthan, Filip Segers, Sverre Holm, Ana Quiles-Jiménez, Ida Gregersen, Cathrine Fladeby, Pål Aukrust, Magnar Bjørås, Arne Klungland, Bente Halvorsen, Ingrun Alseth.
Deletion of Endonuclease V Suppresses Chemically Induced Hepatocellular Carcinoma.
Nucleic Acids Res. 2020 May 7.
Danielle N Alfano, Linda R Klei, Hanna B Klei, Matthew Trotta, Peter J Gough, Kevin P Foley, John Bertin, Tina L Sumpter, Peter C Lucas, Linda M McAllister-Lucas.
MALT1 Protease Plays a Dual Role in the Allergic Response by Acting in Both Mast Cells and Endothelial Cells.
J Immunol. 2020 May 1.
Mathieu Milh, Pierre Roubertoux, Najoua Biba, Julie Chavany, Adeline Spiga Ghata, Camille Fulachier, Stephan Christopher Collins, Christel Wagner, Jean-Christophe Roux, Binnaz Yalcin, Marie-Solenne Félix, Florence Molinari, Pierre-Pascal Lenck-Santini, Laurent Villard.
A knock-in mouse model for KCNQ2-related epileptic encephalopathy displays spontaneous generalized seizures and cognitive impairment.
Epilepsia. 2020 May.
Flavia Amadeu de Oliveira, Sonoko Narisawa, Massimo Bottini, José Luis Millán.
Visualization of Mineral-Targeted Alkaline Phosphatase Binding to Sites of Calcification In Vivo.
J Bone Miner Res. 2020 Apr 28.
Benoit de Pins, Enrica Montalban, Peter Vanhoutte, Albert Giralt, Jean-Antoine Girault.
The Non-Receptor Tyrosine Kinase Pyk2 Modulates Acute Locomotor Effects of Cocaine in D1 Receptor-Expressing Neurons of the Nucleus Accumbens.
Sci Rep. 2020 Apr 20.
Inwoo Hwang, Jee-Yin Ahn.
Dysregulation of Epigenetic Control Contributes to Schizophrenia-Like Behavior in Ebp1 +/- Mice.
Int J Mol Sci. 2020 Apr 9.
Benjamin J Dunmore, XuDong Yang, Alexi Crosby, Stephen Moore, Lu Long, Christopher Huang, Mark Southwood, Eric D Austin, Amer Rana, Paul D Upton, Nicholas W Morrell.
4PBA Restores Signalling of a Cysteine-substituted Mutant BMPR2 Receptor Found in Patients With PAH.
Am J Respir Cell Mol Biol. 2020 Apr 7.
Jamie O Brett, Marina Arjona, Mika Ikeda, Marco Quarta, Antoine de Morrée, Ingrid M Egner, Luiz A Perandini, Heather D Ishak, Armon Goshayeshi, Daniel I Benjamin, Pieter Both, Cristina Rodríguez-Mateo, Michael J Betley, Tony Wyss-Coray, Thomas A Rando.
Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1.
Nat Metab. 2020 Apr.
Martin Kolev, Erin E West, Natalia Kunz, Daniel Chauss, E Ashley Moseman, Jubayer Rahman, Tilo Freiwald, Maria L Balmer, Jonas Lötscher, Sarah Dimeloe, Elizabeth C Rosser, Lucy R Wedderburn, Katrin D Mayer-Barber, Andrea Bohrer, Paul Lavender, Andrew Cope, Luopin Wang, Mariana J Kaplan, Niki M Moutsopoulos, Dorian McGavern, Steven M Holland, Christoph Hess, Majid Kazemian, Behdad Afzali, Claudia Kemper.
Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells.
Immunity. 2020 Mar 17.
Nakawesi J, This S, Hütter J, Boucard-Jourdin M, Barateau V, Muleta KG, Gooday LJ, Thomsen KF, López AG, Ulmert I, Poncet D, Malissen B, Greenberg H, Thaunat O, Defrance T, Paidassi H, Lahl K.
αvβ8 integrin-expression by BATF3-dependent dendritic cells facilitates early IgA responses to Rotavirus.
Mucosal Immunol. 2020 Mar 11.
Geoffrey Parriott, Kelsey Deal, Shane Crean, Elle Richardson, Emily Nylen, Amorette Barber.
T-cells Expressing a chimeric-PD1-Dap10-CD3zeta Receptor Reduce Tumour Burden in Multiple Murine Syngeneic Models of Solid Cancer.
Immunology. 2020 Mar 7.
Nobuaki Fukuma, Eiki Takimoto, Kazutaka Ueda, Pangyen Liu, Miyu Tajima, Yu Otsu, Taro Kariya, Mutsuo Harada, Haruhiro Toko, Kaori Koga, Robert M Blanton Jr, Richard H Karas, Issei Komuro.
Estrogen Receptor-α Non-Nuclear Signaling Confers Cardioprotection and Is Essential to cGMP-PDE5 Inhibition Efficacy.
JACC Basic Transl Sci. 2020 Mar 4.
Sophie J Bradley, Colin Molloy, Paulina Valuskova, Louis Dwomoh, Miriam Scarpa, Mario Rossi, Lisa Finlayson, Kjell A Svensson, Eyassu Chernet, Vanessa N Barth, Karolina Gherbi, David A Sykes, Caroline A Wilson, Rajendra Mistry, Patrick M Sexton, Arthur Christopoulos, Adrian J Mogg, Elizabeth M Rosethorne, Shuzo Sakata, R A John Challiss, Lisa M Broad, Andrew B Tobin.
Biased M1-muscarinic-receptor-mutant Mice Inform the Design of Next-Generation Drugs.
Nat Chem Biol. 2020 Mar.
Werner Y, Mass E, Ashok Kumar P, Ulas T, Händler K, Horne A, Klee K, Lupp A, Schütz D, Saaber F, Redecker C, Schultze JL, Geissmann F, Stumm R.
Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke.
Nat Neurosci. 2020 Mar.
Vorbach S, Gründer A, Zhou F, Koellerer C, Jutzi JS, Simoni M, Riccetti L, Valk PJ, Sanders MA, Müller-Tidow C, Nofer JR, Pahl HL, Potì F.
Enhanced expression of the sphingosine-1-phosphate-receptor-3 causes acute myelogenous leukemia in mice.
Leukemia. 2020 Mar.
Chen C, Sun MA, Warzecha C, Bachu M, Dey A, Wu T, Adams PD, Macfarlan T, Love P, Ozato K.
HIRA, a DiGeorge Syndrome Candidate Gene, Confers Proper Chromatin Accessibility on HSCs and Supports All Stages of Hematopoiesis.
Cell Rep. 2020 Feb 18.
Hesham Soliman, Ben Paylor, R Wilder Scott, Dario R Lemos, ChihKai Chang, Martin Arostegui, Marcela Low, Christina Lee, Daniela Fiore, Paola Braghetta, Vendula Pospichalova, Christina E Barkauskas, Vladimir Korinek, Alessandra Rampazzo, Kathleen MacLeod, T Michael Underhill, Fabio M V Rossi.
Pathogenic Potential of Hic1-Expressing Cardiac Stromal Progenitors.
Cell Stem Cell. 2020 Feb 6.
ElTanbouly MA, Zhao Y, Nowak E, Li J, Schaafsma E, Le Mercier I, Ceeraz S, Lines JL, Peng C, Carriere C, Huang X, Day M, Koehn B, Lee SW, Silva Morales M, Hogquist KA, Jameson SC, Mueller D, Rothstein J, Blazar BR, Cheng C, Noelle RJ.
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance.
Science. 2020 Jan 17.
Matheis F, Muller PA, Graves CL, Gabanyi I, Kerner ZJ, Costa-Borges D, Ahrends T, Rosenstiel P, Mucida D.
Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss.
Cell. 2020 Jan 9.
Zhou L, Flores J, Noël A, Beauchet O, Sjöström PJ, LeBlanc AC.
Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice.
Acta Neuropathol Commun. 2019 Dec 16.
Scott RW, Arostegui M, Schweitzer R, Rossi FMV, Underhill TM.
Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration.
Cell Stem Cell. 2019 Dec 5.
Liu Q, Li M, Whiteaker P, Shi FD, Morley BJ, Lukas RJ.
Attenuation in Nicotinic Acetylcholine Receptor α9 and α10 Subunit Double Knock-Out Mice of Experimental Autoimmune Encephalomyelitis.
Biomolecules. 2019 Dec 4.
Hyo Rim Ko, Inwoo Hwang, Eun-Ju Jin, Taegwan Yun, Dongryeol Ryu, Jong-Sun Kang, Kye Won Park, Joo-Ho Shin, Sung-Woo Cho, Kyung-Hoon Lee, Keqiang Ye, Jee-Yin Ahn.
Roles of ErbB3-binding Protein 1 (EBP1) in Embryonic Development and Gene-Silencing Control.
Proc Natl Acad Sci U S A. 2019 Dec 3.
Shcherbakov D, Teo Y, Boukari H, Cortes-Sanchon A, Mantovani M, Osinnii I, Moore J, Juskeviciene R, Brilkova M, Duscha S, Kumar HS, Laczko E, Rehrauer H, Westhof E, Akbergenov R, Böttger EC.
Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis.
Commun Biol. 2019 Oct 17.
Lipinski S, Pfeuffer S, Arnold P, Treitz C, Aden K, Ebsen H, Falk-Paulsen M, Gisch N, Fazio A, Kuiper J, Luzius A, Billmann-Born S, Schreiber S, Nuñez G, Beer HD, Strowig T, Lamkanfi M, Tholey A, Rosenstiel P.
Prdx4 limits caspase-1 activation and restricts inflammasome-mediated signaling by extracellular vesicles.
EMBO J. 2019 Oct 15.
Pisella LI, Gaiarsa JL, Diabira D, Zhang J, Khalilov I, Duan J, Kahle KT, Medina I.
Impaired regulation of KCC2 phosphorylation leads to neuronal network dysfunction and neurodevelopmental pathology.
Sci Signal. 2019 Oct 15.
Watanabe M, Zhang J, Mansuri MS, Duan J, Karimy JK, Delpire E, Alper SL, Lifton RP, Fukuda A, Kahle KT.
Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival.
Sci Signal. 2019 Oct 15.
Johnston RJ, Su LJ, Pinckney J, Critton D, Boyer E, Krishnakumar A, Corbett M, Rankin AL, Dibella R, Campbell L, Martin GH, Lemar H, Cayton T, Huang RY, Deng X, Nayeem A, Chen H, Ergel B, Rizzo JM, Yamniuk AP, Dutta S, Ngo J, Shorts AO, Ramakrishnan R, Kozhich A, Holloway J, Fang H, Wang YK, Yang Z, Thiam K, Rakestraw G, Rajpal A, Sheppard P, Quigley M, Bahjat KS, Korman AJ.
VISTA is an acidic pH-selective ligand for PSGL-1.
Nature. 2019 Oct.
Oberbeck N, Pham VC, Webster JD, Reja R, Huang CS, Zhang Y, Roose-Girma M, Warming S, Li Q, Birnberg A, Wong W, Sandoval W, Kőműves LG, Yu K, Dugger DL, Maltzman A, Newton K, Dixit VM.
The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.
Nature. 2019 Oct.
Burgener AV1, Bantug GR, Meyer BJ, Higgins R, Ghosh A, Bignucolo O, Ma EH, Loeliger J, Unterstab G, Geigges M, Steiner R, Enamorado M, Ivanek R, Hunziker D, Schmidt A, Müller-Durovic B, Grählert J, Epple R, Dimeloe S, Lötscher J, Sauder U, Ebnöther M, Burger B, Heijnen I, Martínez-Cano S, Cantoni N, Brücker R, Kahlert CR, Sancho D, Jones RG, Navarini A, Recher M, Hess C.
SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2.
Nat Immunol. 2019 Oct.
Helmer RA, Kaur G, Smith LA, Chilton BS.
Helicase-like transcription factor (Hltf) gene-deletion promotes oxidative phosphorylation (OXPHOS) in colorectal tumors of AOM/DSS-treated mice.
PLoS One. 2019 Aug 28.
Paggio A, Checchetto V, Campo A, Menabò R, Di Marco G, Di Lisa F, Szabo I, Rizzuto R, De Stefani D.
Identification of an ATP-sensitive potassium channel in mitochondria.
Nature. 2019 Aug.
Sen NE, Canet-Pons J, Halbach MV, Arsovic A, Pilatus U, Chae WH, Kaya ZE, Seidel K, Rollmann E, Mittelbronn M, Meierhofer D, De Zeeuw CI, Bosman LWJ, Gispert S, Auburger G.
Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation.
Neurobiol Dis. 2019 Jul 31.
Dvela-Levitt M, Kost-Alimova M, Emani M, Kohnert E, Thompson R, Sidhom EH, Rivadeneira A, Sahakian N, Roignot J, Papagregoriou G, Montesinos MS, Clark AR, McKinney D, Gutierrez J, Roth M, Ronco L, Elonga E, Carter TA, Gnirke A, Melanson M, Hartland K, Wieder N, Hsu JC, Deltas C, Hughey R, Bleyer AJ, Kmoch S, Živná M, Barešova V, Kota S, Schlondorff J, Heiman M, Alper SL, Wagner F, Weins A, Golub TR, Lander ES, Greka A.
Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy.
Cell. 2019 Jul 25.
Nathanson AJ, Zhang Y, Smalley JL, Ollerhead TA, Rodriguez Santos MA, Andrews PM, Wobst HJ, Moore YE, Brandon NJ, Hines RM, Davies PA, Moss SJ.
Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures.
Cell Rep. 2019 Jul 16.
Hurtado Del Pozo C, Ruiz HH, Arivazhagan L, Aranda JF, Shim C, Daya P, Derk J, MacLean M, He M, Frye L, Friedline RH, Noh HL, Kim JK, Friedman RA, Ramasamy R, Schmidt AM.
A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis.
Cell Rep. 2019 Jul 16.
Rothweiler S, Feldbrügge L, Jiang ZG, Csizmadia E, Longhi MS, Vaid K, Enjyoji K, Popov YV, Robson SC.
Selective deletion of ENTPD1/CD39 in macrophages exacerbates biliary fibrosis in a mouse model of sclerosing cholangitis.
Purinergic Signal. 2019 Jun 26.
Ali SA, Hanks JE, Stebbins AW, Cohen ST, Hunter DA, Snyder-Warwick AK, Mackinnon SE, Kupfer RA, Hogikyan ND, Feldman EL, Brenner MJ.
Comparison of Myelin-Associated Glycoprotein With Vincristine for Facial Nerve Inhibition After Bilateral Axotomy in a Transgenic Thy1-Gfp Rat Model.
JAMA Facial Plast Surg. 2019 Jun 20.
Dierickx P, Emmett MJ, Jiang C, Uehara K, Liu M, Adlanmerini M, Lazar MA.
SR9009 has REV-ERB-independent effects on cell proliferation and metabolism.
Proc Natl Acad Sci U S A. 2019 Jun 18.
DiCarlo GE, Aguilar JI, Matthies HJ, Harrison FE, Bundschuh KE, West A, Hashemi P, Herborg F, Rickhag M, Chen H, Gether U, Wallace MT, Galli A.
Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors.
J Clin Invest. 2019 May 16.
Wosczyna MN, Konishi CT, Perez Carbajal EE, Wang TT, Walsh RA, Gan Q, Wagner MW, Rando TA.
Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle.
Cell Rep. 2019 May 14.
Ben Khalaf N, Al-Mashoor W, Saeed A, Al-Mehatab D, Taha S, Bakhiet M, Fathallah MD.
The mouse intron-nested gene, Israa, is expressed in the lymphoid organs and involved in T-cell activation and signaling.
Mol Immunol. 2019 May 13.
Grandoch M, Flögel U, Virtue S, Maier JK, Jelenik T, Kohlmorgen C, Feldmann K, Ostendorf Y, Castañeda TR, Zhou Z, Yamaguchi Y, Nascimento EBM, Sunkari VG, Goy C, Kinzig M, Sörgel F, Bollyky PL, Schrauwen P, Al-Hasani H, Roden M, Keipert S, Vidal-Puig A, Jastroch M, Haendeler J, Fischer JW.
4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue.
Nat Metab. 2019 May.
Daniele Bolognini, Natasja Barki, Adrian J Butcher, Brian D Hudson, Eugenia Sergeev, Colin Molloy, Catherine E Moss, Sophie J Bradley, Christian Le Gouill, Michel Bouvier, Andrew B Tobin, Graeme Milligan.
Chemogenetics defines receptor-mediated functions of short chain free fatty acids.
Nat Chem Biol. 2019 May.
Amini SE, Gouyer V, Portal C, Gottrand F, Desseyn JL.
Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.
Histochem Cell Biol. 2019 Apr 27.
Sendžikaitė G, Hanna CW, Stewart-Morgan KR, Ivanova E, Kelsey G.
A DNMT3A PWWP mutation leads to methylation of bivalent chromatin and growth retardation in mice.
Nat Commun. 2019 Apr 23.
Xu W, Cherrier DE, Chea S, Vosshenrich C, Serafini N, Petit M, Liu P, Golub R, Di Santo JP.
An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials.
Immunity. 2019 Apr 16.
Reinicke AT, Laban K, Sachs M, Kraus V, Walden M, Damme M, Sachs W, Reichelt J, Schweizer M, Janiesch PC, Duncan KE5, Saftig P, Rinschen MM, Morellini F, Meyer-Schwesinger C.
Ubiquitin C-terminal hydrolase L1 (UCH-L1) loss causes neurodegeneration by altering protein turnover in the first postnatal weeks.
Proc Natl Acad Sci U S A. 2019 Apr 16.
Lim R, Sugino T, Nolte H, Andrade J, Zimmermann B, Shi C, Doddaballapur A, Ong YT, Wilhelm K, Fasse JWD, Ernst A, Kaulich M, Husnjak K, Boettger T, Guenther S, Braun T, Krüger M, Benedito R, Dikic I, Potente M.
Deubiquitinase USP10 regulates Notch signaling in the endothelium.
Science. 2019 Apr 12.
Kvarnhammar AM, Veitonmäki N, Hägerbrand K, Dahlman A, Smith KE, Fritzell S, von Schantz L, Thagesson M, Werchau D, Smedenfors K, Johansson M, Rosén A, Åberg I, Winnerstam M, Nyblom E, Barchan K, Furebring C, Norlén P, Ellmark P.
The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation.
J Immunother Cancer. 2019 Apr 11.
Leschik J, Eckenstaler R, Endres T, Munsch T, Edelmann E, Richter K, Kobler O, Fischer KD, Zuschratter W, Brigadski T, Lutz B, Lessmann V.
Prominent Postsynaptic and Dendritic Exocytosis of Endogenous BDNF Vesicles in BDNF-GFP Knock-in Mice.
Mol Neurobiol. 2019 Mar 30.
Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ.
Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA.
Cell Rep. 2019 Mar 26.
Tang S, Liu B, Liu M, Li Z, Liu J, Wang H, Wang J, Oh YT, Shen L, Wang Y.
Ionizing radiation-induced growth in soft agar is associated with miR-21 upregulation in wild-type and DNA double strand break repair deficient cells.
DNA Repair (Amst). 2019 Mar 23.
Carneros D, Santamaría EM, Larequi E, Vélez-Ortiz JM, Reboredo M, Mancheño U, Perugorria MJ, Navas P, Romero-Gómez M, Prieto J, Hervás-Stubbs S, Bustos M.
Cardiotrophin-1 is an anti-inflammatory cytokine and promotes IL-4-induced M2 macrophage polarization.
FASEB J. 2019 Mar 20.
Huang K, Ru B, Zhang Y, Chan WL, Chow SC, Zhang J, Lo C, Lui WY.
Sertoli cell-specific coxsackievirus and adenovirus receptor knockout regulates cell adhesion and gene transcription via β-catenin inactivation and Cdc42 activation.
FASEB J. 2019 Mar 20.
Svärd J, Røst TH, Sommervoll CEN, Haugen C, Gudbrandsen OA, Mellgren AE, Rødahl E, Fernø J, Dankel SN, Sagen JV, Mellgren G.
Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice.
Sci Rep. 2019 Mar 15.
Goren I, Köhler Y, Aglan A, Pfeilschifter J, Beck KF, Frank S.
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genOway is author of the following publications:
Henri-Philippe Konan, Loay Kassem, Soleilmane Omarjee, Ausra Surmieliova-Garnès, Julien Jacquemetton, Elodie Cascales, Amélie Rezza, Olivier Trédan, Isabelle Treilleux, Coralie Poulard, Muriel Le Romancer.
ERα-36 Regulates Progesterone Receptor Activity in Breast Cancer.
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Johnston RJ, Su LJ, Pinckney J, Critton D, Boyer E, Krishnakumar A, Corbett M, Rankin AL, Dibella R, Campbell L, Martin GH, Lemar H, Cayton T, Huang RY, Deng X, Nayeem A, Chen H, Ergel B, Rizzo JM, Yamniuk AP, Dutta S, Ngo J, Shorts AO, Ramakrishnan R, Kozhich A, Holloway J, Fang H, Wang YK, Yang Z, Thiam K, Rakestraw G, Rajpal A, Sheppard P, Quigley M, Bahjat KS, Korman AJ.
VISTA is an acidic pH-selective ligand for PSGL-1.
Nature. 2019 Oct.
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Frontline Science: Exhaustion and senescence marker profiles on human T cells in BRGSF-A2 humanized mice resemble those in human samples.
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Rezza A, Jacquet C, Le Pillouer A, Lafarguette F, Ruptier C, Billandon M, Isnard Petit P, Trouttet S, Thiam K, Fraichard A, Chérifi Y.
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Akbergenov R, Duscha S, Fritz AK, Juskeviciene R, Oishi N, Schmitt K, Shcherbakov D, Teo Y, Boukari H, Freihofer P, Isnard-Petit P, Oettinghaus B, Frank S, Thiam K, Rehrauer H, Westhof E, Schacht J, Eckert A, Wolfer D, Böttger EC.
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Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases.
Genome Res. 2014 Jul 2.
Ménoret S, Fontanière S, Jantz D, Tesson L, Thinard R, Rémy S, Usal C, Ouisse LH, Fraichard A, Anegon I.
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Generation of fertile cloned rats by regulating oocyte activation.
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Article in Book:
"Procedures for somatic cell nuclear transfer in the rat" Jean Cozzi, Eryao Wang, Christelle Jacquet, Alexandre Fraichard, Yacine Cherifi, Qi Zhou. Methods and Protocols, Methods in Molecular Biology, vol 597, Humana Press 2010
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"Pronuclear DNA injection for the production of transgenic rats". Cozzi J, Fraichard A, Braun V, Gross A-C, Merrouche C, Anegon I, Thiam K. In: Transgenesis, Third Edition. 2008
"in vivo RNA interference: another tool in the Box?" in Non-viral Gene Therapy - Gene design and Delivery. Taira, K.; Kataoka, K.; Niidome, T. (Eds.) @ Springer-verlag Tokyo 2005