Humanized Immune Checkpoint (ICP) Cell Line Models

Humanized Immune Checkpoint Cell Lines

Humanized immune checkpoint cell lines can be used for in vivo tumor growth assays in syngeneic models and in vitro mechanistic studies.

  • Biosafety level BSL1, according to parental cell line provider guidelines
  • Studies can be carried out at your site or at your favorite CRO
  • Models provided with FTO on patent-protected technologies used for model generation

Humanized tumor cell lines for syngeneic models

If you are looking for other targets, get in touch with us.

hPD-1-hTIM3

Target: PD‑L1          

The MC38-hPD-L1 clonal tumor cell line expresses high levels of human PD-L1, and forms solid tumors in vivo. These cells only express the human PD-L1 as they are invalidated for murine Pd‑l1.

CT26-hPD-1L

Target: PD‑L1          

The CT26-hPD-L1 clonal tumor cell line expresses human PD-L1. Learn more