Immune Checkpoint Catalog Cell Lines

Humanized Immune Checkpoint Cell Lines

Humanized and Knockout immune checkpoint cell lines can be used for in vivo tumor growth assays in syngeneic models and in vitro mechanistic studies.

  • Biosafety level BSL1, according to Kerafast guidelines (parental cell line provider)
  • Studies can be carried out at your site or at your favorite CRO
  • Models provided with FTO on patent-protected technologies used for model generation

Humanized tumor cell lines for syngeneic models


Target: PD‑L1          

The MC38-hPD-L1 clonal tumor cell line expresses high levels of human PD-L1, and forms solid tumors in vivo. These cells only express the human PD-L1 as they are invalidated for murine Pd‑l1. Learn more


Knockout tumor cell lines

MC38-pd-l1 Knockoput cells

Target: Pd‑l1          

The MC38-Pd-l1 clonal tumor cell line is invalidated for murine Pd-l1, and show impaired in vivo tumor growth upon subcutaneous injection in fully immunocompetent mice. Learn more

If you are looking for another target, get in touch with us.