Mice With Humanized Immune Targets

Humanized Mouse Catalog

Our humanized models are well-established mouse lines that allow in vivo efficacy and safety assessment of biologics and other compounds.

  • Cohorts available upon request
  • Studies can be carried out at your site or at your favorite CRO
  • SOPF certification and worldwide delivery by professional breeders
  • Models provided with FTO on patent-protected technologies used for model generation

T-cell Engager

hCD3εhCD3ε/hCD28

  • Enables the in vivo efficacy assessment of T-cell engagers in fully immunocompetent mice

Inflammation and Allergy

hCD4

  • In vivo efficacy and safety assessment of anti-human CD4 compounds
  • Typically used in the fields of inflammation, autoimmune diseases, immuno-oncology, and HIV infection

hIgE + FcεR1

  • Double humanization for IgE and Fcε receptor 1
  • Screen for innovative therapeutics for allergy, asthma, and other IgE-mediated diseases

hTNF-α

  • In vivo efficacy and safety assessment of anti-human TNF-α compounds in the field of autoimmune diseases and inflammation